Introduction

How ADHD hurts the pocket

ADHD is a costly, chronic disorder, with significant impact on the quality of life of patients and their families. The burden of disease is significant, with the Disability Adjusted Life Years (DALYs) calculated as 424 per 100 000. Significant comorbidity contributes to the burden of disease and reduced quality of life of patients with ADHD. 

ADHD and structure – a challenge worth mastering

Multiple studies have been conducted around the impact of ADHD on the brainand the resulting effects onfunctioning. The exactpathophysiology is not clear, however, factors that are thought to contribute to ADHDinclude irregularities in neurotransmitters,brain structures and cognitive functioning.

Biological markers in ADHD: 

Current perspectives and future directions The two initial driving forces in finding biological markers for neurodevelopmental conditions and disorders come from the demands of researchers and parents.

Bio-markers are important in research to establish homogeneity among subjects. In research, the diluting effect of heterogeneity reduces effect sizes and renders identified bio-markers obsolete. Any test that focuses on one domain only, will have limited diagnostic value, but if bio-markers could present a better method for subtyping and improving study designs, they could be very important and beneficial. Unfortunately studies often are complicated by environmental factors, which are seldom evaluated scientifically

Attention deficit hyperactivity disorder and exercise

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental condition occurring in childhood, which in around two thirds of cases, persists into adolescence and adulthood, with significant symptoms still being reported by affected individuals. The genetic heritability is well recognised and is consistently reported across studies to be around 75- 80

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ADHD Briefcase - Edition 2 - 2021